Handbook of Basic Pharmacokinetics

First published in 1976, the Handbook of Basic Pharmacokinetics...Including Clinical Applications is known for being a user-friendly consolidation of pharmacokinetic principles and techniques for practitioners, researchers, and students that merits a place in any personal or college library. In this seventh edition, 10 chapters have been substantially revised to address recent developments and incorporate new information, illustrations, and equations and up-to-date literature citations. The appendix has been expanded to include parameters for some 150 additional drugs, bringing the total to more than 790. Key Features: Chapters on the following topics have been updated: Absorption/Transport Mechanisms, Physicochemical and Biological Factors Affecting in vivo Performance of Drugs, Drug Biotransformation, Excretion and Clearance of Drugs, Pediatric Pharmacokinetics, First-Dose Size in Man, Correlation of Clinical Response with Drug Disposition, Bioavailability and Bioequivalence, Extracorporeal Methods of Drug Removal, and Pharmacogenetics and Pharmacogenomics. More than 100 pharmacokinetic terms are defined in Chapter 1. Pharmacokinetic data compiled from the literature on nearly 800 drugs-150 new to this edition-are presented in the tabular appendix.