Extracellular Matrix and The Liver : Approach to Gene Therapy

Extracellular Matrix of the Liver addresses the basic science of the extracellular matrix and discusses new strategies for the treatment of cirrhosis of the liver, with a primary focus on possible gene therapy approaches. The chapters are divided into six sections as follows: Basic Science of Extracellular MatrixCells Responsible for Extracellular Matrix ProductionActivation Mechanism of Hepatic Cells and Signal TransductionBasic Science for Extracellular Matrix Metabolism including Enzymes and their InhibitorsMatrix Mettaloproteinases and Tissue Inhibitors for Matrix Mettaloproteinases New Strategies for the treatment of Liver CirrhosisDiscusses the possibility of gene therapy for liver cirrhosisIncludes information on new aspects of hepatic stellate cellsWritten by top experts in basic science and clinical hepatology