Bioinformatics in the Post-Genomic Era : Genome, Transcriptome, Proteome, and Information-Based Medicine

"Augen's book provides a thorough review of bioinformatics that presages the coming era of information-based medicine." John Reynders, VP of Informatics, Celera Genomics "Augen is to be congratulated on producing an indispensable book. He not only lays out and explains the essential tools in bioinformatics, but he also validates the critical role that computational biology will play in the future of medical research. This is a fabulous achievementthere is something here for novice and expert alike." Kevin Davies, Editor-in-Chief, Bio-IT World "Jeff has created an erudite, yet amazingly accessible overview of the intersection between biology, biomedicine, and high-performance computing." Andrea Califano, Director, Genome Center Bioinformatics, Columbia University "This book is essential for anyone wishing to understand the information technology transformation of the life sciences." W.R. Pulleyblank, Director, Deep Computing Institute, IBM Research "Because of its unusually broad scope, Jeff Augen's new book has the capacity to deliver value to a wide variety of audiences. As a longtime investor in biotechnology and healthcare, I find the discussions surrounding the future of medicine and information technology particularly interesting and useful." G. Steven Burrill, Chief Executive Officer, Burrill and Company "Augen takes you on a complete guided tour of computational biology, combining historical perspectives with discussions of the leading-edge technologies being employed today. This book would be useful for anyone in the field. It provides an entire overview to scientists new to computational biology, while giving experts detailed information about new developments in the field." Salvatore Salamone, Senior IT Editor, Bio-IT World and Health-IT World "There are books about bioinformatics with a focus on information technology and books on molecular biology with a focus on bioscience, but I am not aware of any book that provides a summary of fundamentals of both bioscience and information science with a technical bridge between the two disciplines. This book is unique in covering theoretical and practical aspects of bioinformatics. Everyone from biologists and geneticists to computer scientists and engineers will benefit from Augen's book." O.K. Baek, Chief Architect, Biomedical Informatics and Information-Based Medicine, IBM Today, advances in high-performance computing, data management, and the Internet are transforming many aspects of biomedical research and have produced a new generation of tools for studying gene and protein sequences, macromolecular structures, and metabolic systems. These tools have greatly accelerated the drug discovery and testing process and promise to change the way diseases are predicted and treated in the future. Bioinformatics in the Post-Genomic Era is the first comprehensive lo...