Cavernous Malformations

Cavernous malformations can lead to significant neurologic symptoms - from nerve pain, weakness and coordination difficulties to visual loss, memory deficits, and speech impairment, and even extending as far as intractable epilepsy and paralysis. At 3-7% incidence in the general population is small but significant, yet the current literature does not offer comprehensive, up-to-date coverage of this condition. This volume it the HCN series is an evidence-based compendium which addresses both the scientific and clinical aspects of this unique disease process. The volume covers didactic aspects, such as the epidemiology, etiology, and diagnosis of cavernous malformations, while also providing expert clinical information on the management and treatment of these lesions. In addition, it provides coverage of modern-day advances in the genetics of cavernous malformations, as well as discussion regarding future open research questions. Readers from the laboratory bench to the bedside can expect a broad yet objective review of this pathology, with updates from the latest scientific literature and data supporting current practices. * Offers an evidence-based focus with coverage of both the scientific and clinical aspects of cavernous malformations* Addresses epidemiology, etiology, diagnosis, and genetics* Clinical insights regarding indications for surgery, surgical techniques, outcomes, and prognostic factors drawn from the authors' extensive experiences* Edited work with chapters authored by leaders in the field around the globe - the broadest, most expert coverage available