Umpoled Synthons : A Survey of Sources and Uses in Synthesis

The purpose of this book is to provide chemists who plan their synthetic routes manually with information on some of the new umpoled synthons. The introductory chapter examines, in general, the use of synthons in planning organic syntheses. Concluding the introduction is a fairly detailed list of generally convenient synthons that are, however, extraneous to the main contents of the book. A major portion of the book is devoted to acyl anions, hydroxycarbonyl and related anions, carbonyl-cations and carbonyl-anions. A further group comprises carbanionic synthons in which the carbon atom carries a singly bonded heteroatom (O,S,N, or halogen). In appropriate chapters, the above synthons are surveyed with emphasis on the aspects relating to synthetic use. The book concludes with a tabular presentation of known applications of these synthons, with relevant data on the sources, auxiliary reagents, yields and restrictions.