Unconjugated pterins and related biogenic amines : proceedings of the First International Workshop, Flims, Switzerland, february 28 - march 7, 1987

Frontmatter -- PREFACE -- ACKNOWLEDGEMENTS -- CONTENTS -- In Memoriam ALOIS NIEDERWIESER (1935 - 1987) / Curtius, H.-Ch. -- SECTION A: CHEMISTRY AND ANALYSIS OF PTERINS -- HOMOGENEOUS CATALYTIC HYDROGENATION OF L-BIOPTERIN: INFLUENCE OF THE CHIRALITY OF THE SIDE CHAIN AND THE CATALYST ON ITS DIASTEREOSELECTIVE INDUCTION / Antoulas, S. / Viscontini, M. -- SYNTHESIS OF D-NEOPTERIN-3'-PHOSPHATES / Zagalak, B. / Neuheiser, F. / Bosshard, R. / Redweik, U. -- 5-ALKYL-5.6.7.8-TETRAHYDROBIOPTERINS / Kaiser, A. -- MASS SPECTROMETRIC INVESTIGATIONS OF PTERIDINES / Kuster, Th. / Niederwieser, A. -- THE STRUCTURAL CHARACTERIZATION OF 6-PYRUVOYL TETRAHYDROPTERIN BY FAST ATOM BOMBARDMENT MASS SPECTROMETRY WITH ONE- AND TWO-DIMENSIONAL MASS ANALYSIS (FAB/MS AND FAB/MSMS) / Richter, W.J. / Raschdorf, F. / Dahinden, R. / Niederwieser, A. / Curtius, H.-Ch. / Leimbacher, W. / Kuster, Th. -- SECTION : BIOCHEMISTRY AND METABOLISM OF PTERINS -- TETRAHYDROBIOPTERIN: OTHER PHYSIOLOGICAL ROLES IN ADDITION TO AROMATIC AMINO ACID HYDROXYLATION? / Milstien, Sheldon -- 1H-NMR STUDIES WITH TETRAHYDROBIOPTERINS, EVIDENCE FOR THE STRUCTURE OF 6-PYRUVOYLTETRAHYDROPTERIN, AN INTERMEDIATE IN THE BIOSYNTHESIS OF TETRAHYDROBIOPTERIN / Ghisla, S. / Steinerstauch, P. / Hasler, Th. / Blau, N. / Curtius, H.-Ch. -- PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN SYNTHASE FROM SALMON LIVER / Hasler, Th. / Niederwieser, A. / Curtius, H.-Ch. -- PURIFICATION OF 6-PYRUVOYL TETRAHYDROPTERIN 2'-KETO REDUCTASE FROM HUMAN LIVER / Curtius, H.-Ch. / Steinerstauch, P. / Leimbacher, W. / Redweik, U. / Takikawa, Sh.-I. / Ghisla, S. -- HUMAN GTP CYCLOHYDROLASE I: PURIFICATION AND PREPARATION OF MONOCLONAL ANTIBODIES / Schoedon, G. / Niederwieser, A. / Curtius, H.-Ch. -- DIHYDROMONAPTERIN TRIPHOSPHATE: OCCURRENCE, ANALYSIS, AND EFFECT ON TETRAHYDROBIOPTERIN BIOSYNTHESIS in vivo AND in vitro / Blau, N. / Steinerstauch, P. / Redweik, U. / Pfister, K. / Schoedon, G. / Kierat, L. / Niederwieser, A. -- BIOSYNTHESIS OF PTERIDINES AND DEAZA FLAVINS IN METHANOGENIC BACTERIA / Schwarzkopf, B. / Le Van, Q. / Eisenreich, W. / Keller, P. J. / Floss, H. G. / Bacher, A. -- TETRAHYDROBIOPTERIN BIOSYNTHESIS AND PTERIDINE METABOLISM IN CELLS OF THE BLOOD SYSTEM, LYMPHOID TISSUES AND IN BIOLOGICAL FLUIDS / Andondonskaja-Renz, B. / Zeitler, H.-J. -- MODIFIED PTERIPINE SYNTHESIS IN TRANSFORMED CELL LINES AND DURING HEAT SHOCK / Seidl, J. / Przybylski, M. / Meinschad, Ch. / Ziegler, I. -- DISEASE ASSOCIATED ALTERATIONS OF PTERIN BIOSYNIHESIS: ENHANCEMENT IN INFLAMMATORY DISEASE, HEMOPOIETIC REGENERATION AND ENDOTOXINEMIA / Huber, Ch. / Herold, M. / Troppmair, J. / Rokos, H. -- METABOLISM OF PTERINS IN THE CELLULAR IMMUNE SYSTEM OF MAN AND MOUSE / Schoedon, Gabriele / Niederwieser, Alois / Curtius, Hans-Christoph / Fontana, Adriano / Troppmair, Jacob / Huber, Christoph -- TETRAHYDROBIOPTERIN SYNTHESIS IS TRIGGERED BY INTERLEUKIN 2 BINDING AND MODULATES RECEPTOR AFFINITY / Ziegler, Irmgard -- KINETICS OF PRODUCTION AND RELEASE OF NEOPTERIN. COMPARISON OF HUMAN PBMC WITH THE PERMANENT MONOCYTIC CELL LINE U937 AND ITS SUBCLONES. / Rokos, K. / Kunze, R.O.F. / Koch, .A. / Rokos, H. / Nilsson, K. -- SECTION D: PTERINS IN DIFFERENT DISEASES -- VARIATIONS OF NEOPTERIN, DIHYDRONEOPTERIN AND IMMUNOLOGICAL PARAMETERS DURING PHYSICAL EXERCISE (JOGGING) / Rokos, H. / Rokos, K. / Kunze, R.O.F. -- BIOPTERIN AND NEOPTERIN IN PLASMA AND LYMPHO-MONONUCLEAR BIOPTERIN IN GRAFT VERSUS HOST DISEASE AND INFECTION AFTER BONE MARROW TRANSPLANTATION. / Fink, M. / Nüssler, V. / Demtröder, . / Höniges, . / Kolb, H.J. / Ziegler, I. -- EFFECTS OF IRENZEPINE, ACICLOVIR AND TRIMETHOPRIM ON PTERINS IN BLOOD CELLS AND PLASMA / Fink, M. / Nüssler, V. / Demtröder, . / Höniges, . / Goldberg, . -- SECTION : TETRAHYDROBIOPTERIN DEFICIENCIES -- HETEROGENEITY OF TETRAHYDROBIOPTERIN DEFICIENCY / DHONDT, Jean-Louis -- PRENATAL DIAGNOSIS OF TETRAHYDROBIOPTERI DEFICIENCY / Blau, N. / Niederwieser, A. / Curtius, H.Ch. / Leimbacher, W. / Kierat,