Structure, Function and Regulation of Molecules Involved in Leucocyte Adhesion : Proceedings of the Second International Conference "Structure and Function of Molecules Involved in Leucocyte Adhesion

Bok av P E Lipsky
Leukocyte adhesion molecules have been the subject of intense basic and preclinical research. Results from clinical trials with antibodies directed towards these surface proteins offer promise for the prevention of graft rejection and effective treatment of acute and chronic inflammatory disease. This volume presents a review of contemporary research on the structure, function and regulation of leukocyte adhesion molecules and their ligands, from the molecular to the clinical level. The blend of basic science and clinical applications presented in the text provides evidence of the biological importance of cell-cell interactions and the many potential clinical dividends afforded by understanding the molecular basis of cell adhesion.