Anti-Tussive Activity of In-House Designed and Marketed Formulation : Development and Standardization of Formulation

For evaluation of granules containing different herb parameters tested for raw material were organoleptic, physicochemical, physical, phytochemical etc. Parameters for finished product (granules) include pH, LOD, angle of repose, tapped density, bulk density, Carr's index, Hausner's ratio. Marketed formulation consists of aqueous extract of G. glabra, Z. officinalis and A. vasica indicated for sore throat, cough, cold and flu. Results indicated that Raw material of Marketed formulation and Developed formulation were identical with respect to all organoleptic, physicochemical, physical, and phytochemical parameters. All three batches of marketed formulation were uniform in colour, size, loss on drying, angle of repose, bulk and tap density and also showed uniformity with developed formulation. HPTLC fingerprinting indicated presence of peaks at Rf in respective solvent system were matched with Raw material, Marketed formulation and Developed formulation confirm.