Adverse Health Effects of Passive Smoking : Passive Smoking, Lung Function and Plasma Cytokines among School Pupils

Exposure to second-hand tobacco smoke at home (passive smoking) has been linked to many complications, including impaired lung function and altered plasma cytokines. In this study, the relationship between regular secondhand smoke exposure at home and the spirometric derived values forced expiratory volume in the first second (FEV1), forced vital capacity (FVC), forced expiratory flow 50% and peak expiratory flow rate were determined among school pupils in Khartoum, Sudan. Plasma levels of TNFa, IL4 and CRP were assessed and analysed to determine their relation to impaired lung function among passive smokers. Results of this study indicate that passive smoking has a significant impact on lung function and plasma cytokines. The results should be presented in educational programs to increase awareness of parents about the negative impact and serious complications of passive smoking on child's health.