Modeling of Blood Flow in Stenosed Lad Coronary Artery : Angiographical Investigation and Numerical Simulation

Atherosclerosis is the most common causes of vascular diseases.So;looking for the physical factors and correlations that explain the phenomena of existence the atherosclerosis disease in LAD artery in some people rather than the others is achieved in this study by analysis data from coronary angiography as well as estimating the blood velocity from coronary angiography scans without having a required data on velocity by using some mathematical equations and physical laws. It found some information that may explain the ability of small arteries to develop the lesions with time mainly in proximal site of LAD artery. For investigation the fluid-structural response to pulsatile Newtonian and non-Newtonian blood flow through an axisymmetric stenosed coronary artery;the simulation is built up by using ANSYS11 to evaluate the biomechanical parameters in the atherosclerotic process. Rigid and Newtonian cases were investigated to provide an understanding on the effects of incorporating Fluid-Structural Interaction (FSI) into model. non-Newtonian Carreau model was investigated with FSI. For validation of the models and methods used, the computation results are compared with previous studies.