Fiziologicheskie Reaktsii Immunnoy Sistemy U Studentov Severnykh Vuzov

Obuchenie v vuzakh na Severe pred"yavlyaet vysokie trebovaniya k zdorov'yu studentov, sostavlyayushchikh sotsial'nuyu gruppu naseleniya, skhodnuyu po vozrastu, usloviyam truda, byta i otdykha. Klimaticheskie usloviya zhizni severyan, adaptatsiya k kompleksu novykh faktorov, spetsifichnykh dlya vysshey shkoly, soprovozhdaetsya znachitel'nym napryazheniem kompensatorno-prisposobitel'nykh sistem organizma studentov, v t.ch. immunnoy. V rabote dan detal'nyy nauchnyy analiz chastoty registratsii i variantov immunnykh disbalansov u studentov mladshikh i starshikh kursov priarkticheskikh VUZov. Immunodefitsit u studentov nachal'nykh kursov ne vosstanavlivaetsya s vozrastom, usugublyaetsya u studentov starshikh kursov i proyavlyaetsya manifestnymi formami ekologicheski zavisimykh immunodefitsitov. Narastanie urovney soderzhaniya aktivirovannykh T-limfotsitov u studentov v protsesse obucheniya idyet preimushchestvenno za schyet kletok s retseptorom CD25+, CD71+ i HLA-DR+, v usloviyakh T-kletochnogo defitsita CD5+ i nizkogo urovnya differentsirovki T-kletok. V dinamike obucheniya u studentov v perifericheskoy krovi uvelichivaetsya soderzhanie provospalitel'nykh tsitokinov (IL-1; IL-4; TNF-).