Candidal Infection : Prevention and Treatment

Candidiasis is the commonest fungal disease in human being. The causative agent of the disease is Candida albicans and non- albicans Candida. Candida has 163 acknowledged anamorphic species, present on the different habitat out of which following species are C. albicans, C. tropicalis, C. krusei, C. glabrata, C. guilliermondii, C. parapsilosis, C. lusitaniae, C. kefyr, C. rugosa, C. dubliniensis and C. viswanathii known to causing disease in human beings. The virulence factors of the C. albicans have the great role in the pseudohyphae formation by attached with epithelial cells and endothelial cells. Now a day various techniques like PCR, Candida Detection System, CAND-TEC and Dot Immunobinding Assay are available for detection of candidiasis from various clinical samples. The CHROM agar Candida is useful method to differentiate between the Candida albicans and other species of the genus Candida by the help of colonies colour of the Candida on culture plate. Keeping skin clean, dry, and free from abrasions or cuts can help prevent skin from Candidal infections. The animal pathogenicity of Candida has been observed in few animals like rabbit and mice.