Diagnosticheskie Markery Porazheniya Pochek U Novorozhdennykh S Asfiksiey

Rabota posvyashchena izucheniyu tsennosti razlichnykh biomarkerov dlya diagnostiki porazheniya pochek u novorozhdennykh s asfiksiey. Rassmatrivaetsya rol' syvorotochnogo tsistatina S i ego preimushchestva pered traditsionnym ispol'zovaniem kreatinina syvorotki dlya opredeleniya skorosti klubochkovoy fil'tratsii. Dlya topicheskoy diagnostiki povrezhdeniya pochechnoy tkani otsenivaetsya soderzhanie ryada fermentov syvorotki krovi. V kachestve neinvazivnykh markerov osveshchaetsya znachenie opredeleniya v moche u novorozhdennykh urovnya laktatdegidrogenazy, gamma-glutamiltranspeptidazy, interleykina-18. Otdel'nyy razdel posvyashchen kristallograficheskim markeram porazheniya pochek u novorozhdennykh s asfiksiey.