Development of Mucoadhesive, Unidirectional Control Release Tablets

Mucoadhesion of the developed formulations will provide a longer period of residence time reducing loss of drug by swallowing, which should result in higher bioavailability.The mucoadhesive tablets of cefuroxime axetil can prolong release of drug across the mucous membrane of intestine and can increase residence time of drug. That can improve its bioavailability and may reduce its dosing frequency and side effects.