Platelet Rich Fibrin and Periodontal Tissue Regeneration

Platelets play an important role in periodontal regeneration as they contain growth factors and cytokines which are essential for bone regeneration and soft tissue maturation. Platelet-rich plasma (PRP) and platelet-rich fibrin (PRF) are autologous platelet concentrates prepared from patient's own blood. PRF is second generation platelet concentrate which is prepared without any artificial biochemical modification of blood. It is biocompatible, easy to prepare, economical and enriched with platelets and growth factors. This book reviews the properties of PRF and its potential role in periodontal regeneration.