Melatonin I Retinoevaya Kislota Kak Morfogeny Planariy

Protsessy rosta i razvitiya, morfogeneza i regeneratsii u zhivotnykh yavlyayutsya neot"emlemymi sistemami ontogeneticheskogo razvitiya i podderzhaniya zhiznesposobnosti organizma. Oni osushchestvlyayutsya putem mnogourovnevogo kontrolya s mnozhestvom triggerov, pryamykh i obratnykh svyazey, v osnove kotorykh lezhat geneticheskie mekhanizmy, realizuyushchiesya na kletochnom, tkanevom i organizmennom urovnyakh. Odnimi iz regulyatorov morfogeneza yavlyayutsya veshchestva - morfogeny. Nastoyashchaya rabota predstavlyaet issledovanie morfogeneticheskoy roli melatonina i retinoevoy kisloty v protsessakh regeneratsii i morfogeneza planariy. Eksperimental'nyy analiz vozdeystviya etikh veshchestv na regulyatsiyu protsessov razvitiya i rosta u planariy pozvolit rasshirit' predstavleniya o stepeni adekvatnosti i primenimosti dannoy biologicheskoy modeli dlya issledovaniya morfogeneticheski aktivnykh veshchestv.