Ekspressiya SS- I Skhs-Khemokinov I Ikh Retseptorov U Bol'nykh Ibs

Bok av Nil'k Rostislav Yaroslavovich

Ustanovleno, chto u bol'nykh ishemicheskoy bolezn'yu serdtsa ekspressiya khemokinov i khemokinovykh retseptorov v krovi nizhe po sravneniyu so zdorovymi litsami. Opredelena otritsatel'naya korrelyatsionnaya svyaz' mezhdu ekspressiey otdel'nykh khemokinov ili ikh retseptorov v krovi s urovnem obshchego kholesterina i global'noy sokratitel'noy sposobnost'yu miokarda levogo zheludochka. Dlya bol'nykh s dlitel'nym anamnezom ishemicheskoy bolezni serdtsa kharakterna nizkaya ekspressiya ryada khemokinov i khemokinovykh retseptorov v krovi, tkanyakh aorty, luchevoy arterii i bol'shoy podkozhnoy veny. Vyyavlennye assotsiatsii mezhdu ekspressiey khemokinov, khemokinovykh retseptorov i osobennostyami ishemicheskoy bolezni serdtsa svidetel'stvuyut ob uchastii sistemy khemokinov v razvitii i progressirovanii zabolevaniya.