Sintez Geterotsiklicheskikh Soedineniy

Propinali, v tom chisle, kremniysoderzhashchie, yavlyayutsya udobnymi stroitel'nymi blokami dlya sinteza funktsional'nykh geterotsiklov (lekarstvennykh sredstv, sensorov, schityvayushchikh ustroystv, preobrazovateley solnechnoy energii i dr.). V knige izlozheny podkhody k sintezu novykh mono- i bis-geterotsiklicheskikh soedineniy v reaktsiyakh kremniy-, germaniysoderzhashchikh propinaley s N,O-, N,S-, N,N-binukleofilami i trimetilsililazidom. V zavisimosti ot usloviy reaktsiy polucheny neizvestnye ranee azometiny, 1,3-tiazolidiny, oksimy elementsoderzhashchikh propinaley i ikh uglerodnykh analogov. Realizovany novye trekhkomponentnye reaktsii elementsoderzhashchikh propinaley s trimetilsililazidom i pervichnymi aminami (2-aminoetantiolom, 2-amino-5-metiltiazolom i 4-aminoantipirinom), pozvolyayushchie poluchat' neizvestnye ranee azotsoderzhashchie bis-geterotsiklicheskie soedineniya s neskol'kimi farmakofornymi funktsiyami. Otmecheno znachitel'noe uskorenie, a v nekotorykh sluchayakh izmenenie selektivnosti protsessov, pod deystviem mikrovolnovogo izlucheniya. Kniga prednaznachena dlya khimikov, spetsializiruyushchikhsya v oblasti elementoorganicheskoy khimii, a takzhe mozhet byt' polezna shirokomu krugu nauchnykh rabotnikov i studentov.