Vzaimodeystvie Faktorov Terminatsii Translyatsii S Razlichnymi Belkami

Bok av Askinazi Ol'ga
V nastoyashchee vremya vedetsya poisk genov, produkty kotorykh mogut vzaimodeystvovat' s faktorami terminatsii translyatsii. Poisk takikh genov delaet vozmozhnym vyyavlenie svyazi translyatsii s drugimi protsessami v kletke. Dannaya rabota posvyashchena izucheniyu vzaimodeystviya belkov Ecm23, Gic2 i Nab2 s faktorami terminatsii translyatsii eRF1 i eRF3 drozhzhey Saccharomyces cerevisiae. Osnovyvayas' na poluchennykh rezul'tatakh, avtory predpolagayut, chto dannye belki yavlyayutsya posrednikami mezhdu faktorami terminatsii translyatsii i kaskadom aktivatsii protsessa psevdogifal'nogo rosta drozhzhey. _____________________________________________________________ Many laboratories of the world are now searching for the proteins that can interact with the translation termination factors. The search for those proteins gives possibilities to identify connections between translation and other cellular processes. This research is dedicated to the study of the proteins Ecm23, Gic2, and Nab2 and their interaction with the yeast translation termination factors eRF1 and eRF1. Authors suggest that these proteins can act as triggers between translation termination factors and the signaling pathway of yeast pseudohyphal growth activation.