Medium : A study on physiological changes in Elderly with Special Reference to Age-Related Cognitive Deficit and its management

Aging is the process of becoming older, a process that is genetically determined and environmentally modulated. When broadly defined, aging refers to all time-associated events that occur during old age. These changes may be beneficial, neutral or deteriorative. During the developmental period of life most changes are due to maturation of physiological processes and tend to be beneficial. However, in the post maturation period of life, most of these changes are detrimental.Centella asiatica has been reported to accelerate nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in vitro. Axonal regeneration is important for functional recovery. Centella asiatica ethanolic extract elicited a marked increase in neurite outgrowth in human SH- SY5Ycells in presence of nerve growth factors. Greatest activity was found with a non- polar fraction (GKF4). (Soumyanath et al. 2005).